FA Cup Quarter-Final Southampton vs Arsenal: Three Key Factors To Consider, Predicted Lineups and Team News

Southampton vs Arsenal should turn out to be a thrilling clash as these two sides meet in the quarterfinals of the 2025/26 FA Cup and look to gain a berth in Wembley Stadium after their clash at St. Mary’s Stadium on Saturday evening.

The Southampton vs Arsenal clash should be pretty tightly fought between the Premier League leaders and the underdogs from the EFL Championship. Southampton look to pull off a huge upset with a powerful performance against the Premier League giants, while the Gunners aim to get back to winning ways with a dominant victory to move forward in the FA Cup.

Match Details

St. Mary’s Stadium
Southampton, England
Saturday, April 4
19:00 GMT

Unpredictable Southampton Looking To Pull Off Surprise Win Over Arsenal

The Southampton vs Arsenal game should be a pretty entertaining clash because of how determined both sets of players are towards reaching the semifinals of the FA Cup.

Southampton have showcased a lot of grit in their performances in the FA Cup this season, getting narrow wins over the likes of Leicester City and Fulham to set up their battle against the Premier League leaders in the quarterfinals.

Now, Southampton will need to produce a particularly efficient performance in being defensively rock-solid and also take their chances in an efficient manner to produce a real upset. Arsenal are, meanwhile, looking to get back to winning ways after suffering a dismal loss in the Carabao Cup final to Manchester City in their previous game.

The Gunners have impressed in the FA Cup this season with some comfortable victories, but they’ll face a stern test in the quarterfinals, and Mikel Arteta needs his side to be at their ruthless best to get a commanding win.

The Gunners have won two of their last five matches against Southampton, and look to get another win over the Saints with a prolific display at St. Mary’s.

Can Finn Azaz Uplift Southampton Towards Inspiring Win Over Arsenal?

With Adam Armstrong having left Southampton midway through the 2025/26 season, a lot of responsibility has been thrown onto the shoulders of Finn Azaz to lift them towards victories.

The 25-year-old has been enjoying a pretty good campaign personally with 10 goals and six assists in the 2025/26 EFL Championship, and he’s also managed to bag an assist in two FA Cup appearances so far for the Saints.

Now, it’s time for Azaz to level up his performances if he really aspires to torment the Arsenal backline. He’ll need to be smart with his attacking movement and link-up play to help his side take the fight to the Gunners, and Azaz also needs to be clinical in finishing off whatever chances come his way to inspire Southampton to a positive result in the FA Cup quarterfinal.

Determined Viktor Gyokeres Aiming To Bring Positive International Form to FA Cup

Viktor Gyokeres had a brilliant March (2026) international break, as he helped Sweden win both their FIFA World Cup 2026 qualifiers to earn a place in the competition.

He’s scored three goals in his last two appearances for Sweden, and is determined to put the underwhelming performance in the Carabao Cup behind him by being a tormenting factor against Southampton.

Gyokeres has 16 goals in all competitions for Arsenal so far this season, but he is yet to actually score in an FA Cup game for Arsenal. The Swedish striker will be determined to end that barren run against Southampton, troubling their defenders with his movement and physicality and also use his predatory instincts towards scoring crucial goals to help Arsenal reach the FA Cup semi-finals.

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Wrexham FC v Chelsea, FA Cup Chelsea huddle during the FA Cup match between Wrexham FC and Chelsea at the Racecourse Ground, Wrexham, UK on 7 March 2026. Wrexham Racecourse Ground Wales UK Editorial use only DataCo restrictions apply See www.football-dataco.com , Copyright: xAlunxRobertsx PSI-23863-0181

Southampton vs Arsenal Injuries

Southampton Injuries: Mads Roerslev, Leo Scienza (doubt), Wellington (doubt), Jay Robinson (doubt)

Arsenal Injuries: Eberechi Eze, Mikel Merino, Piero Hincapie, William Saliba (doubt), Jurrien Timber (doubt), Gabriel Magalhaes (doubt), Leandro Trossard (doubt), Noni Madueke (doubt), Martin Zubimendi (doubt)

Southampton vs Arsenal Predicted Lineups

Here are our Southampton vs Arsenal predicted lineups.

Southampton Predicted XI: Daniel Peretz (GK), James Bree, Taylor Harwood-Bellis, Nathan Wood, Ryan Manning, Flynn Downes, Cameron Bragg, Tom Fellows, Finn Azaz, Kuryu Matsuki, Ross Stewart

Arsenal Predicted XI: David Raya (GK), Ben White, Christhian Mosquera, Gabriel Magalhaes, Riccardo Calafiori, Christian Norgaard, Declan Rice, Bukayo Saka, Kai Havertz, Gabriel Martinelli, Viktor Gyokeres

Main Photo

Credit: IMAGO / Every Second Media

Recording Date: 14.03.2026

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