Manchester United vs Chelsea is set to be the standout fixture in the Premier League on Saturday, September 20, as both sides are eager to get back to winning ways in their highly anticipated clash at Old Trafford.
The Red Devils are aiming to make a strong return to action in front of their devoted supporters after their recent loss in the Manchester Derby, while Chelsea look to bounce back from their recent defeat to Bayern Munich in the UEFA Champions League to get their Premier League title aspirations back on track.
With that being said, here we look at a few key factors to consider for the upcoming Manchester United vs Chelsea clash in the Premier League.
Manchester United vs Chelsea Match Details
Old Trafford Stadium
Manchester, England
20 September, 2025
Kickoff 4:30 PM GMT
Inconsistencies
Manchester United have been riddled with inconsistency at the start of their 2025/26 Premier League campaign. In fact, they have only been able to win one game out of four, with that coming at Old Trafford against Burnley.
With just four points from as many games, Ruben Amorim continues to face pressure over his job amid speculation that he might be sacked if results don’t improve. He’ll need to motivate his players to be way more ruthless and produce an inspired display in front of their home faithful to end Chelsea’s unbeaten run in the Premier League.
Chelsea have had a bump in their early stages of the new campaign with some disappointing results in recent games. They were held to a frustrating draw by Brentford in the previous league game before suffering a dismal loss to Bayern Muninch.
Enzo Maresca needs his side to get their groove back, and a commanding win at Old Trafford could be exactly what is needed for Chelsea to get their winning momentum back.
Can Sloppy Manchester United Attack Finally Wake Up?
Even though Manchester United might have only scored four goals in as many Premier League matches so far, it’s not like they’ve been totally boring and inefficient.
The Red Devils have had over 100 shot attempts in the league this season, out of which 70 have been on target. However, the fact that only four goals have been scored out of all that shows which issues need to be fixed quickly.
The Red Devils need their new signing, Bryan Mbeumo, who has two goals so far, and Benjamin Sesko, who has none, to be livelier and much more clinical in the final third.
Their positioning needs to be right, but the attacking players at Manchester United need to be more ruthless with their finishing and the positioning of their shots to trouble Robert Sanchez.
If the Red Devils players can be more clinical in accurately finishing off all the chances being created, they could put on a real show against Chelsea.
Cole Palmer Eager To Continue Heroics Against Manchester United
The good thing for Chelsea fans is that Cole Palmer looks to be back to his best, having scored in their last two matches.
The even better thing is that the Englishman loves playing against Manchester United, having won three of the five matches he’s played against them in his career. Palmer has scored four goals in as many games he’s started against the Red Devils.
Who can forget his amazing hat trick against the Red Devils at Stamford Bridge in Chelsea’s 4-3 win over the Manchester side in the 2023/24 season?
Palmer has hit his stride at the perfect moment, and Enzo Maresca will hope he can continue tormenting the Red Devils. Palmer, a self-admitted Manchester United fan as a child, will look to put on a spectacle at Old Trafford by timing his runs perfectly and be prolific in finishing off whatever chances come at his disposal to guide Chelsea to a win.
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Manchester United vs Chelsea Key Injuries
Manchester United injuries: Matheus Cunha, Diogo Dalot, Mason Mount, Lisandro Martinez
Chelsea injuries: Levi Colwill, Liam Delap, Benoit Badiashile, Romeo Lavia, Dario Essugo
Manchester United vs Chelsea Predicted Lineups
Knowing the importance of this Premier League clash, both Ruben Amorim and Enzo Maresca will look to field the strongest starting lineups.
Here we look at the Manchester United vs Chelsea predicted lineups:
Manchester United Predicted XI: Senne Lammens, Noussair Mazraoui, Matthijs de Ligt, Leny Yoro, Amad Diallo, Casemiro, Bruno Fernandes, Patrick Dorgu, Bryan Mbeumo, Kobbie Mainoo, Benjamin Sesko
Chelsea Predicted XI: Robert Sanchez, Reece James, Wesley Fofana, Trevoh Chalobah, Marc Cucurella, Moises Caicedo, Enzo Fernandez, Estevao Willian, Cole Palmer, Pedro Neto, Joao Pedro
Main Photo
Credit: IMAGO / Sportimage
Recording Date: 14.09.2025