The Liverpool vs Southampton clash should be an exciting one as the Reds are determined to keep their 100% win record in the 2025/26 going as they face off against Championship side Southampton at Anfield in the third round of the 2025/26 Carabao Cup encounter on Tuesday, 23 September.
The Reds might opt to rest some crucial senior players in this game, but they still boast enough quality and depth in their squad to be able to put on a dominant display against the struggling Southampton side.
Liverpool vs Southampton Match Details
Anfield Stadium
Liverpool, England
23 September, 2025
Kickoff 7 PM GMT
A Polarising Tale of Two Teams on Opposite Spectrums
The Liverpool vs Southampton battle will be a case of two sides who are basically polarising opposites of one another in terms of form and momentum.
Liverpool have won all six of their matches in the 2025/26 season so far, including all five of their Premier League games to keep their place on top of the table. Moreover, they have also won their only UEFA Champions League match so far against Atletico Madrid, despite yet to having tapped into their best form.
Things couldn’t be more opposite for Southampton in the EFL Championship. The Saints have had a sloppy start to the 2025/26 Championship campaign, being able to win only one of their first six matches. They are lingering in 19th place in the Championship table and on the back of a dismal loss to Hull City before their trip to Anfield.
Because of the difference in momentum and confidence for both sets of players, this Carabao Cup clash should be a highly enticing clash with the possibility of multiple results.
Can Alexander Isak Open His Account For Liverpool?
The Carabao Cup clash against Southampton can be the ideal game for Alexander Isak to properly introduce himself to the Anfield favourite.
After having completed his record-setting transfer to Liverpool, the Swedish forward has made two appearances for Liverpool, but has not been able to score any goals for them so far. Fortunately for the Reds, Isak has a thing for performing in Carabao Cup matches.
Who can forget Isak’s heroics in helping Newcastle United win the 2024/25 Carabao Cup, scoring a key goal against Liverpool in the final? The Swedish forward should get to start against Southampton and will be determined to score his first Liverpool goal.
He will aim to take advantage of the shaky Southampton defensive shape to find openings in the final third and get at the end of opportunities to finish them off emphatically and get some pressure off his back.
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How Can Southampton Upset Liverpool At Anfield?
A herculean task is in front of Southampton if they really aspire to defeat this undefeated Liverpool side at their own yard in the upcoming clash. Southampton doesn’t really have a strong enough defensive line to even aspire to park the bus against Liverpool, who have enough quality to even break that up if necessary.
What Will Still can really do is to motivate his side to take the fight to the Reds. He needs his players to capitalise on Liverpool’s vulnerability against fast-paced transitions and needs his forwards to be rapid on the counterattacks to trouble the defenders.
He’ll also need his players to be at their ruthless best and finish off chances emphatically to have any chance of earning a positive result from Anfield.
Liverpool vs Southampton Key Injuries
Liverpool Injuries: Stefan Bajcetic
Southampton Injuries: Samuel Edozie, Wellington
Liverpool vs Southampton Predicted Lineups
Even though there should be tweaks to both sides in the Liverpool vs Southampton clash, both Arne Slot and Will Still will look to field strong teams to bolster their chances of winning.
Here we look at the Liverpool vs Southampton predicted lineups.
Liverpool Predicted XI: Giorgi Mamardashvili, Jeremie Frimpong, Joe Gomez, Giovanni Leoni, Andy Robertson, Wataru Endo, Alexis Mac Allister, Mohamed Salah, Florian Wirtz, Rio Ngumoha, Alexander Isak
Southampton Predicted XI: Gavin Bazunu (GK), Mads Roerslev, Jack Stephens, Taylor Harwood-Bellis, Ryan Manning, Flynn Downes, Shea Charles, Adam Armstrong, Finn Azaz, Ryan Fraser, Cameron Archer
Main Photo
Credit: IMAGO / Sportimage
Recording Date: 17.09.2025