Liverpool vs Real Madrid is one of the stand-out fixtures to open Matchday 4 of the 2025/26 UEFA Champions League, taking place on Tuesday, November 4 at Anfield.
The Liverpool vs Real Madrid clash is loaded with narrative. Liverpool are trying to get back on track after mixed results, while Real Madrid – under Xabi Alonso this season – look dangerous and confident. On paper, Madrid have a historical edge. But at Anfield, anything can happen.
Match Details
Anfield
Liverpool, England
Tuesday, November 4
20:00 GMT
Unsettled Liverpool Seek Stability Against In-Form Madrid
The Reds enter the Liverpool vs Real Madrid match with questions in defence and attack. Their form has been erratic: they have only two wins in their last eight matches.
And while, their win against Aston Villa was strong, it was a side did not amplify Liverpool’s weaknesses. Their other win in those eight matches was against Frankfurt in the UCL, another game where Liverpool’s vulnerability to the long ball went unexposed.
Real Madrid, meanwhile, have been more consistent this season, and Alonso’s side are riding high, with only one loss so far in all competitions.
Anfield is a fortress though. Over the years Liverpool have been overwhelming in home group games. Liverpool have won 20 of their last 22 Champions League group-stage matches at Anfield. That gives them hope. But Madrid also arrive with momentum and attacking threats.
Across all competitions, Real Madrid have the better head-to-head record: Madrid have won seven, Liverpool three, with one draw.
Can Liverpool Cope With Their Missing Pieces?
Injury news hurts Liverpool heading into this tie. Alisson Becker remains out with a hamstring injury.
Jeremie Frimpong is also ruled out with a hamstring issue, and will reportedly be out for another month. Alexander Isak and Curtis Jones are also still out, both struggling with groin problems.
This forces Arne Slot to pick from a slimmer pot for the Liverpool vs Real Madrid clash. The defence will need to stand strong without key personnel, and the attack must still find the cutting edge under pressure.
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Madrid’s Depth and Defensive Challenges
Ahead of the Liverpool vs Real Madrid game, Los Blancos aren’t without issues either. They will be missing multiple defenders: Dani Carvajal (knee surgery) and Antonio Rudiger (muscle) are confirmed out. David Alaba is dealing with a calf issue, keeping him out as well.
On top of that, 18-year-old attacker Franco Mastantuono has been ruled out with pubalgia, a fresh blow to their attacking options.
Yet they still have power in depth. Their midfield and frontline remain dangerous, with players like Arda Guler, Vinicius Jr, Kylian Mbappe and Jude Bellingham able to change a game. Guler, having appeared to pick up an ankle knock, is now cleared and available.
Liverpool vs Real Madrid Injuries
Liverpool injuries: Alisson, Jeremie Frimpong, Alexander Isak, Curtis Jones, Giovanni Leoni
Real Madrid injuries: Antonio Rudiger, Dani Carvajal, David Alaba, Franco Mastantuono
Liverpool vs Real Madrid Predicted Lineups
With so many absences, Arne Slot and Xabi Alonso may be forced into compromises. All factors considered, here, we look at the Liverpool vs Real Madrid predicted lineups:
Liverpool predicted XI: Giorgi Mamardashvili, Conor Bradley, Ibrahim Konate, Virgil van Dijk, Andy Robertson, Alexis Mac Allister, Ryan Gravenberch, Mohamed Salah, Cody Gakpo, Florian Wirtz, Hugo Ekitike
Real Madrid predicted XI: Thibaut Courtois, Trent Alexander-Arnold, Eder Militao, Dean Hujsen, Alvaro Carreras, Federico Valverde, Auriel Tchouameni, Arda Guler, Vinicius Jr, Jude Bellingham, Kylian Mbappe
Main Photo
Credit: IMAGO / Alberto Gardin
Recording Date: 01.11.2025