Tottenham vs Manchester United: Three Key Factors, Predicted Lineups To Consider, Injuries

Tottenham vs Manchester United is going to kick off Gameweek 11 of the 2025/26 Premier League campaign as the two teams fight to get closer to the top spots in the league table in their meeting on Saturday afternoon.

The Tottenham vs Manchester United clash is likely to be a highly entertaining clash between two teams who had quite a few interesting matches last season, with Spurs even defeating the Red Devils in the 2024/25 UEFA Europa League final.

Manchester United are gunning for revenge and look to get another big away win under their belt in the Premier League to pile more misery at the Tottenham Hotspur Stadium for the Lilywhites.

Match Details

Tottenham Hotspur Stadium
London, England
Saturday, November 8
12:30

Under-Pressure Tottenham Hotspur Face Unpredictable Manchester United in Europa League Final Rematch

Because the recent Tottenham vs Manchester United matches have been quite gripping affairs, their upcoming match at the Tottenham Hotspur Stadium should be something similar as well. Spurs are facing pressure from their home fans after only managing to win one match at the Tottenham Hotspur Stadium in the 2025/26 Premier League so far, suffering a dismal loss to Chelsea recently.

Manchester United, meanwhile, have only won one away game in the Premier League this season, and the similar issues within both teams should make this upcoming clash an exciting affair.

Recent Tottenham vs Manchester United matches have been dominated by the Lilywhites, who have won their last four meetings against the Red Devils. The last time that Manchester United defeated Spurs was back in October 2022, and they desperately aim to end their barren run against the North London side in this upcoming clash.

With Ruben Amorim’s side picking up form with 10 goals scored in their last four Premier League matches, they’ll be determined to torment the Spurs backline, while the Lilywhites look to use their counter-attacking brilliance to blow away the Manchester side.

Can Mohammed Kudus Rediscover His Magic To Inspire Tottenham?

Mohammed Kudus has proven himself to be a really good 2025 summer transfer window signing for Tottenham Hotspur, and has become a pivotal player in Thomas Frank’s system. He’s managed four assists and one goal in 10 Premier League matches so far this season and is determined to bring more consistency to his end product against the Red Devils.

Kudus will be aiming to torment Manchester United, whose backline has looked shaky in recent games, conceding five goals in their last three games. Kudus will need to be sharp with his movement to fool the defenders, and also extremely decisive with his crosses or shots on goal to help elevate Tottenham’s attacking threat and inspire them to a big win in their home yard.

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Lively Bryan Mbeumo Hoping for Another Major Away Performance

Bryan Mbeumo has arguably been Manchester United’s best player in the 2025/26 Premier League so far and is proving to be well worth the money they paid to sign him from Brentford in the summer. The Cameroonian winger has already scored four goals in the 2025/26 Premier League for his side, and he boasts a really good record against Spurs too.

Indeed, Mbeumo has scored four goals in seven league games against the Lilywhites when he was at Brentford, and he scored at the Tottenham Hotspur Stadium last season as well.

In this weekend’s Tottenham vs Manchester United clash, Mbeumo will be looking to trouble the Spurs defenders with his unpredictable movement into key areas and drive his way into the danger zones. However, he’ll need to be ruthless with his finishing to stun the Spurs backline and be able to guide Manchester United to another away win.

Tottenham vs Manchester United Injuries

Tottenham injuries: James Maddison, Dejan Kulusevski, Dominic Solanke, Ben Davies, Radu Dragusin, Yves Bissouma, Archie Gray, Kota Takai, Lucas Bergvall

Manchester United injuries: Lisandro Martinez

Tottenham vs Manchester United Predicted Lineups

Knowing the importance of this clash, both Thomas Frank and Ruben Amorim will be aiming to field strong teams. Here, we look at the Tottenham vs Manchester United predicted lineups:

Tottenham Predicted Lineup: Guglielmo Vicario, Pedro Porro, Cristian Romero, Micky van de Ven, Djed Spence, Joao Palhinha, Rodrigo Bentancur, Pape Sarr, Mohammed Kudus, Brennan Johnson, Randal Kolo Muani

Manchester United Predicted Lineup: Senne Lammens, Matthijs de Ligt, Harry Maguire, Luke Shaw, Amad Diallo, Casemiro, Bruno Fernandes, Diogo Dalot, Bryan Mbeumo, Mason Mount, Matheus Cunha

Main Photo

Credit: IMAGO / Visionhaus

Recording Date: 01.11.2025

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